Introduction

 

Tuberculosis is one of the leading causes of mortality in India- killing -2 persons every three minute, nearly 1,000 every day.

Tuberculosis (TB) is a contagious disease caused by Mycobacterium tuberculosis

Left untreated, each person with infectious pulmonary TB will infect an average of between 10 and 15 people every year.

With emergence of Multi Drug Resistance and co-infection with HIV has weakened our battle against the disease.

 

 

 

 

 

 

 

 

Treatment Of MDR-TB Cases

 

RNTCP will be using a Standardised Treatment Regimen (Cat IV) for the treatment of MDR-TB cases (and those with rifampicin resistance) under the programme.

Category: IV

Category of Patients: MDR TB Cases

Intensive Phase: 6-9(kmOfxEtoCsZE)

Continuation phase: 18(OfxEtoCsE)

Km – Kanamycin ;Ofx- Ofloxacin; Eto-Ethionamide ; Cs- Cycloserin; Z- Pyrazinamide ; E- Ethambutol

 

New lines of diagnosis

 

Xpert MTB/RIF has 72 per cent sensitivity with one test, and 90 per cent with three tests in the case of smear-negative patients. The sensitivity goes up to 98 per cent in the case of smear-positive and culture-positive patients. Xpert MTB/RIF has 99 per cent specificity.

It can turn in results in less than two hours compared with four to six weeks in the case of the culture process.

But the most important advantage is its ability to diagnose rifampicin drug resistance.

 

 

 

 

TB Made Notifiable (May 7,2012)

 

Mandatory for laboratories, hospitals, nursing homes and doctors, both in the public and private sector, to report every TB case detected.

Once a case is notified govt. will ensure correct diagnosis and complete adherence to treatment during the entire duration of treatment.

This is where the approaches that India and China adopted to fighting TB diverged.

Of the 37 notifiable diseases in China, TB ranks No. 1. It pulled out all the stops by 2000. “The concept of acceptance of the problem, identifying its requirement and the political will of TB eradication has set China on a progressive path,” notes a paper published in the journal Interdisciplinary Perspectives on Infectious Diseases.